依沙吖啶湿敷对肾病综合征患儿阴囊水肿的作用

The Effect of Ethacridine on Scrotal Edema in Children with Nephrotic Syndrome

目的：回顾性分析依沙吖啶湿敷对肾病综合征患儿阴囊水肿的疗效。方法：对1998年－2008年120例肾病综合征阴囊水肿的患儿分为治疗组和对照组各60例，两组患儿均按肾病常规治疗，对照组患儿阴囊水肿未作处理，治疗组用0．1％依沙吖啶湿敷阴囊。结果：治疗组和对照组阴囊水肿消退时间分别为（5．28±0．65）d和（13．88±3．62）d，治愈时间分别为（5．62±0．73）d和（14．30±4．36）d，两组比较差异均有统计学意义（P〈0．01）。结论：对肾病综合征患儿采用0．1％依沙吖啶湿敷，能防止阴囊水肿的感染，加快阴囊水肿消退，是一种有效的辅助治疗方法和护理手段。

Objective： To study retrospectively the effect of the Ethacridine on scrotal edema in nephrotic syndrome children. Methods： One hundred and twenty nephrotic syndrome children from 1998 to 2008 were divided at random, 60 cases in each group. Both groups were treated with the same conventional therapy of nephrotic syndrome. The scrotums of ethacridine group were hydropathic compressed with 0. 1% ethacridine solution, and the scrotums of the control group were untreated. Results： The time for scrotal edema subsiding of treatment group and control group were （5.28 ±0.65） d and （13.88 ±3.62） d, healing time was （5.62 ±0.73） d and （14.30 ±4.36） d, differences between the two groups were statistically significant （P 〈 0.01 ）. Conclusions： Ethacridine solution （0.1% ） conduces to relieve the scrotal edema and prevent the subsequent infection in children with nephrotic syndrome, and is an effective assistant therapy.