蒲地蓝消炎口服液治疗小儿手足口病的疗效观察

Therapeutic Effects of Pudilan Xiaoyan Oral Liquid on Children with Hand,Foot and Mouth Disease

目的:观察蒲地蓝消炎口服液治疗小儿手足口病的临床疗效。方法:选择门诊176例手足口病患儿随机分成两组,治疗组130例口服蒲地蓝消炎口服液;对照组46例口服利巴韦林颗粒。结果:两组疗效比较,治疗组显效率(57.5%)、总有效率(92.5%)均明显优于对照组(分别为19.4%,69.4%),差异有统计学意义(P<0.01);两组总病程、口腔溃疡好转时间比较差异有统计学意义(P<0.05);两组总热程、用药后热程、皮疹消退时间比较差异有统计学意义(P<0.01)。结论:蒲地蓝消炎口服液治疗手足口病疗效显著,预后良好,能缩短疗程,未见明显不良反应。

Objective： To evaluate the therapeutic effects of Pudilan Xiaoyan oral liquid in children with hand, foot and mouth disease （HFMD）. Methods： One hundred and seventy-six patients with HFMD in our out-patient department were randomly divided into two groups. One hundred and thirty patients in the therapeutic group were treated with Pudilan Xiaoyan oral liquid; 46 patients in the control group were treated with oral ribavirin. Results： The marked effect rate and the total effective rate of the therapeutic group were significantly higher than those of the control group （ P 〈 0.01 ）. The difference in disappearing of main symptom and sign, total course of disease, oral ulcer improvement time was significant （P 〈 0.05 ） between the therapeutic group and the control group. There was a significant difference in total length of fever time, length of fever time after treatment and deflorescence time between the therapeutic group and the control group （P 〈 0.01 ）. Conclusions： Pudilan Xiaoyan oral liquid has a good therapeutic effect in children with HFMD, and shortened duration of HFMD with no complications and adverse reactions.