北京市东城社区40岁以上人群脑动脉狭窄的流行病学调查

Prevalence of Cerebral Arterial Stenosis in Dongcheng Community People Aged Over 40 Years in Beijing

目的研究40岁以上人群脑动脉狭窄的患病率及分布规律和相关危险因素,为我国脑血管病的防治提供依据。方法以社区40岁以上人群为研究对象,采用经颅多普勒超声(transcranial doppler,TCD)和颈动脉双功能彩超检测颅内外动脉,以NASCET方法判断狭窄程度。结果男、女两性及总体颅内外动脉狭窄的患病率均随年龄增长而增高(P<0.01),≥75岁组男性颅内外动脉狭窄率明显高于女性(P=0.01)。应用Logistic回归分析结果显示,性别、年龄、原发性高血压、糖尿病、高血脂、超重和吸烟是脑动脉狭窄的独立危险因素。结论脑动脉狭窄的患病率与性别、年龄、原发性高血压、糖尿病、高血脂、超重和吸烟等有关系,控制上述危险因素对脑动脉狭窄的预防和治疗有一定意义。

Objective To study the prevalence rate, the distribution and related risk factors of cerebral artery stenosis, and provide the basis for the prevention and treatment in cerebrovascular disease in our country. Methods Study the community groups, using transcranial Doppler ultrasound （TCD） and neck artery duplex color Doppler ultrasound to detect intracranial and extracranial arteries, and use NASCET methodology to determine the degree of stenosis. Results The prevalence of intracranial and extracranial artery stenosis increased with age in male, female and overall （P〈0. 01）. The prevalence of intracranial and extracranial artery stenosis was higher in male than in female in the patients older than 75 years （P= 0.01）. Application of Logistic regression, it showed that sex, age, hypertension, diabetes, high blood cholesterol, overweight and smoking was an independent： cerebrovascular risk factor for restenosis. Conclusions The prevalence of artery stenosis connects with sex, age, hypertension, diabetes, high blood cholesterol, overweight and smoking. This study provides a certain guiding function for patients with day-to-day prevention and diagnosis, treatment.