小柴胡颗粒质量标准研究

Study on Quality Standards of Xiaochaihu Granules

目的制订小柴胡颗粒的质量标准。方法采用薄层色谱法对小柴胡颗粒中的黄芩、甘草、党参进行定性鉴别,用高效液相色谱法测定黄芩中黄芩苷的含量。结果黄芩、甘草、党参的定性鉴别灵敏度高、专属性强;黄芩苷含量测定的平均回收率为99.30%,RSD=0.86%(n=6)。结论建立的定性、定量方法简便、准确、灵敏、重现性好。

Objective To make out the quality standards of Xiaochaihu Granules. Methods The identification of compositions in Radix scutel- lariae, Radix Glycyrrhizae and Codonopsis pilosula were carried out with TLC. The baicalin in scutellaria was determined by HPLC method. Results The identification of Radix scutellariae, Radix Glycyrrhizae and Codonopsis pilosula in Xiaochaihu Granules was carried out with TLC. The average recovery rate was 99.30% ,with RSD =0.86%（n=6）. Conclusion The methods proved to be simple,accurate,sensitive and reproducible.