小儿慢性咳嗽与肺炎支原体、肺炎衣原体感染的关系探讨

Investigation on the Relation between Chronic Cough and Mycoplasma Pneumoniae,Chlamydia Pneumoniae Infection in Children

目的探讨小儿慢性咳嗽与肺炎支原体(MP)、肺炎衣原体(CP)感染的关系,为治疗提供依据。方法对确诊的98例小儿慢性咳嗽和60例对照组儿童采用酶联免疫吸附实验检测血浆MP、CP特异性IgM抗体,并进行组间比较。结果研究组MP感染45例(45.9%)、CP感染12例(12.2%);对照组MP感染4例(6.7%)、CP感染2例(3.3%),研究组混合感染5例(5.1%),对照组0例,两组比较差异有统计学意义。结论小儿慢性咳嗽与肺炎支原体、肺炎衣原体感染关系密切,在对慢性咳嗽小儿寻找病因时,应常规进行MP-IgM、CP-IgM的检测,为临床治疗提供依据。

Objective To investigate the relation between children chronic cough and myeoplasma pneumoniae, chlamydia pneumoniae infection,in order to provide a basis for treatment. Methods 98 cases diagnosed as children with chronic cough and 60 cases in control group were detected by enzyme-linked immunosorbent assay of plasma MP, CP-specific IgM antibodies, and group comparison was made. Results MP infection in study group were 45 cases（45.9% ） , CP infection were 12 cases（ 12.2% ） ;MP infection in control group were four eases（6.7% ） ,CP infection 2 eases（3.3% ） ,the mixed infection in study group were 5 cases （5.1% ）, and none in control group, there is statistically significant difference between the two groups. Conclusion The relation between chronic cough in children and mycoplasma pneumoniae, chlamydia pneumoniae infection is close. MP-IgM, CP-IgM should be routinely detected in looking for causes of chronic cough in children, to provide a basis for clinical treatment.