北京市海淀区啮齿类动物中汉坦病毒自然感染状况调查

Investigation on the natural infectious status of Hantaviruses in rodents in Haidian district, Beijing

目的调查海淀区肾综合征出血热(HFRS)疫源地啮齿类动物中汉坦病毒(HV)的自然感染情况,为HFRS针对性的预防和控制提供科学依据。方法用夹夜法在海淀区捕鼠,捕获的啮齿动物进行分类鉴定并解剖取肺脏,同时用间接免疫荧光法检测HV。结果在辖区内共捕获啮齿类动物2属3种225只,褐家鼠为优势鼠种。该区HV自然感染率范围为4.60%～20.00%,平均6.22%。其中不同鼠种自然感染率褐家鼠为6.96%,小家鼠为6.06%,黑线姬鼠为0。结论海淀区啮齿类动物自然感染HV普遍,主要存在以家鼠属为宿主的HV感染。

Objective To investigate the situation of the natural infection of Hantaviruses （HV） in rodents and provide the guidance for the control and prevention of hemorrhagic fever with renal syndrome （HFRS） in Haidian district, Beijing. Methods Rodents were captured by night trap, and lung tissue samples were taken out and stored in liquid Nitrogen. HV was detected by indirect immuno- fluorescence assay （IFA）. Results There were 225 rodents captured in different habitats of Haidian district, which belonged to 3 species and 2 Genera. Rattus norvegicus was the dominant species in the habitats investigated. The total natural infection rates of HV in rodents ranged from 4.60% to 20.00%, and the average was 6.22%. Different species had different natural infection rates. The rate of infection among R.norvegicus and Mus rnusculus was 6.96% and 6.06% respectively, while Apodemus agrarius was not infected. Conclusion The rodents were infected by HV in Haidian district commonly, and its main host was Rattu Genera.