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艾滋病免疫重建炎性综合征并发结核病16例 被引量:2

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摘要 目的探讨艾滋病(AIDS)患者在高效抗逆转录病毒治疗(HAART)中发生免疫重建炎性综合征(IRIS)时并发结核病的临床特征。方法回顾分析16例AIDS患者发生免疫重建炎性综合征(IRIS)时并发结核病的相关临床资料。结果16例病人中4例肺结核出现恶化,2例新出现肺结核,8例出现淋巴结结核,所有病人血CD4+T淋巴细胞均比抗病毒治疗前增加,经继续HAART及联合抗结核治疗后病情均能改善,所有病人均未中止HAART。结论艾滋病患者在进行HAART治疗中,出现发热、淋巴结肿大,伴有或不伴有呼吸道症状,病情反复或加重时,均应考虑患者体内原存在结核杆菌感染而出现结核性免疫重建炎性综合征(TB-IRIS)的可能;对于TB-IRIS,继续原有的HAART并给予标准的抗结核治疗,绝大部分的TB-IRIS患者病情可缓解,一般不须停用HAART,亦无须加用糖皮质激素治疗。
作者 谢毓
出处 《内科》 2009年第5期799-801,共3页 Internal Medicine
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