腹膜假性黏液瘤11例临床分析

Evaluation of 11 patients with peritoneal pseudomyxoma

目的探讨腹膜假性黏液瘤的诊断、治疗和预后。方法总结11例腹膜假性黏液瘤的诊治体会并复习文献加以分析。结果11例患者以腹痛、腹胀、腹部包块及不全肠梗阻为主要表现。大多需多次手术治疗。11例均为阑尾黏液囊肿破裂所致。治疗应早期手术治疗,切除原发灶及尽可能切除腹腔内其他脏器上的黏液性病变,必要时联合脏器部分切除。术后辅助治疗包括化疗、局部腹腔内化疗及放疗。我们强调腹腔化疗。术后随访率100%,10年生存率72.73%(8/11)。结论腹膜假性黏液瘤临床少见,部分预后较差。应早期诊断和早期治疗。

Objective To investigate the diagnosis,treatment and prognosis of peritoneal pseudomyxoma.Methods We summarized the data of 11 patients with peritoneal pseudomyxoma and reviewed the related literature.Results Eleven patients complained of abdominal pain,abdominal distension,abdominal mass,and incomplete intestinal obstruction.Most of the patients were operated on for several times.The 11 patients were due to rupture of the pendiceal mucocele.The operation was done in an early stage to remove original foci and to remove other lesions in the abdomen,or other infected organs if necessary.Adjunctive therapy post-operation included chemotherapy,local abdominal chemotherapy and radiotherapy,with an emphasis of abdominal chemotherapy.The post-operative follow-up rate was 100%,and the 10-year survival rate was 72.73%（8/11）.Conclusion Peritoneal pseudomyxoma is rare and usually has a poor prognosis.It needs early diagnosis and treatment.