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天然产物的代谢工程与菌种改良

Strain Improvement to Produce Bioactive Natural Products by Metabolic Engineering
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摘要 重点讨论天然产物的代谢工程在产量提高、组分优化及产物延伸等方面的进展,说明代谢工程作为生物工程的一个新兴分支可以成为传统育种的重要补充,是在理性思维指导下有目的的菌种定向改良。 This review discusses the recent developments of metabolic engineering in improving yield, controlling component, and extending production, and the applications of this approach for rational strain improvement.
作者 唐功利
机构地区 中国科学院上海有机化学研究所生命有机化学国家重点实验室
出处 《上海化工》 CAS 2009年第10期16-22,共7页 Shanghai Chemical Industry
关键词 生物合成 代谢工程 组分调整 菌种改良 Biosynthesis Metabolic engineering Controlling component Strain improvement
分类号 Q93 [生物学—微生物学]
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上海化工
2009年 第10期

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