摘要
A new polyhydroxysteroidal glycoside, （20R,24R）-16-O-（4-O-methyl-2-acetamido-2-deoxy-β-D-galactopyranosyl）-24-ethyl- 5α-cholest-8（14）-en-313,613,713,16α-tetrol （anthenoside A, 1）, was isolated from the starfish Anthenea chinensis. Its structure was elucidated by extensive spectral analysis and chemical evidences. 1 exhibited significant cytotoxicity against human tumor K-562, BEL-7402 and U87MG cells.
A new polyhydroxysteroidal glycoside, （20R,24R）-16-O-（4-O-methyl-2-acetamido-2-deoxy-β-D-galactopyranosyl）-24-ethyl- 5α-cholest-8（14）-en-313,613,713,16α-tetrol （anthenoside A, 1）, was isolated from the starfish Anthenea chinensis. Its structure was elucidated by extensive spectral analysis and chemical evidences. 1 exhibited significant cytotoxicity against human tumor K-562, BEL-7402 and U87MG cells.
基金
the National Natural Science Foundation of China(No.20502035)
the National High-Tech Research and Development Project(No.2006AA09Z423)
