钙剂辅助缩宫素预防剖宫产产后出血的临床观察

Calglucon in treating postcesarean hemorrhage

目的:观察钙剂辅助缩宫素预防剖宫产产后出血的临床效果。方法:将240例行剖宫产分娩的无血液系统疾病、有剖宫产指征、存在产后出血高危因素的足月妊娠孕产妇随机分为观察组和对照组。观察组:120例,于术前30min应用5%葡萄糖注射液250mL或氯化钠注射液250mL加10%葡萄糖酸钙10mL静脉点滴,胎儿娩出后立即宫体注射缩宫素20U;对照组:120例,胎儿娩出后宫体注射缩宫素20U。检测产后2h内出血量,以容积法及称重法计算出血量,大于400mL为产后出血。结果:产后2h内出血量,观察组为(282±156)mL,对照组为(346±180)mL。观察组术后2h出血量均低于对照组,2组比较有统计学意义(P<0.05)。观察组产后24h血红蛋白平均下降值明显低于对照组(P<0.05)。结论:钙剂辅助缩宫素可减少剖宫产产后出血量,方法简单有效。

OBJECTIVE To explore the effect and safety of using calglucon to treat postcesaren hemorrhage. METHODS The 240 pregnantwoman who were found to have the indications of cesarean section and high risk factors but without cardiovascular diseases were randomly divided into the observation group and the contrast group. 120 case in the observation group were given with intraveneous injection of 10 mL of 10% calglucon 30 minutes before operation,21） U oxytoc in immediately after delivery. 120 case in the contrast group were given with injection of 20 U oxytocin. The amounts of hemorrhage was measured in 2 hours after delivery. RESULTS The amounts of hemorrhage in the observation of group and the contrast group were （282 ± 156）mL and（346± 180）mL respectively （P〈0.05）. CONCLUSION Calglucon can reduce postcesaren hemorrhage effectively.