利用影像融合技术评估肺癌放射治疗全程剂量体积直方图

To evaluate dose volume history in process of lung cancer radiotherapy using image fusion technique completely

目的探讨利用影像融合技术完整的评估肺癌患者放射治疗全程剂量体积直方图参数。方法25例未能手术肺癌患者，中位年龄54岁，Karnofsky评分≥70。均采用三维适形放射治疗，利用CT模拟定位，进行放射治疗40Gy-50Gy后，缩野进行第二次扫描，将两次图像利用ACQsim工作站进行影像融合并重新勾画靶区，并将两次的靶区剂量和正常组织剂量利用放射治疗计划系统相叠加。结果所有患者均完成放射治疗，总剂量60Gy-66Gy，叠加后的剂量体积直方图可以完整的反映出正常肺组织、脊髓及心脏所受剂量。结论根据合成后的DVH，评估正常器官受量，调整放射治疗总剂量，可以最大限度的降低放射治疗并发症的发生。

Objective To evaluate dose volume history in process of lung cancer radiotherapy using image fusion technique completely. Methods 25 patients who did not undergo operations, median age 54 and Karnofsky Performance Status≥70. All received three -dimensional conformal radiation therapy using CT - sim, and were scanned by CT - sim repeatedly after 40 - 50 Gy radiotherapy. We made image fusion of the images before and after radiotherapy using ACQsim working station and overlayed total dose of normal tissues through radiotherapy planning system. Results Radiotherapy was finished for every patient and total dose was 60 -66 Gy. DVH could reflect the suffering dose of normal pulmonary tissue, spinal cord and heart completely. Conclusion Adjustment of total dose during radiotherapy period by the suffering dose of normal tissues could decrease complication occurrence in process of radiotherapy.