胸水多项肿瘤标志物联合检测的临床价值

The Clinical Value of Detecting Tumor Multi-Markers in Pleural Effusion

目的:探讨胸水中多项肿瘤标志物的联合检测对鉴别癌性胸水、炎性胸水的临床价值,以提高癌性胸水的确诊率。方法:采用FJ2008P放免计数器测定40例癌性胸水和51例炎性胸水中的CEA、CA125、SF三种肿瘤标志物含量,进行对比分析。结果:癌性胸水组中CEA、CA125、SF三种肿瘤标志物平均水平明显高于正常值高限,炎性胸水组平均水平低于正常值(P<0.05),肿瘤标志物癌性胸水组阳性率95.00%,炎性胸水组25.48%(P<0.05)。结论:胸水CEA、CA125、SF三种肿瘤标志物联合检测对鉴别良恶性胸水有临床价值。

Objective： To study the clinical value of tumor multi - markers in cancer pleural effusion differing from inflammatory pleural effusion, so as to heighten identification level, to improve diagnosis ability of cancer pleural effusion. Methods：Took RIA counter FJ2008P;there were 40 cases of cancer pleural effusion and 51 cases of inflammatory pleural effusion were analyzed in the CEA, CA125, SF [ three of tumor markers]. Results：CEA, CA125, SF levels of cancer pleura1 effusion group were significantly higher than that of normal average high limit, inflammatory pleural effusion group were below the normal average level （P 〈 0. 05 ）;cancer pleural effusion group had positive rate of 95.00 percent, Inflammatory hydrothorax Group 25.48% （ P 〈 0. 05 ）. Conclusion ： CEA, CA125, SF of tumor markers in Hydrothorax should be combined detection ; three tumor markers for identification of benign and malignant pleura] effusion all have clinical value.