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脂磷壁酸的提取纯化及抑菌活性研究 被引量:1

Study on extraction and anti-bacterial activity of Lipoteichoic acid
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摘要 分别采用TX114和冷酚法提取A群链球菌中的脂磷壁酸(Lipoteichoic acid,LTA),并进行抑菌活性研究。紫外全波长扫描显示,阴离子交换层析分离TX114提取的LTA具有很好的纯度。试验表明,LTA具有良好的抑菌活性,且采用TX114方法的提取效果高于冷酚法。 Lipoteichoic acid(LTA) is extracted from group A streptococcus by adopting TX114 and cold phenol method to study the antibacterial activity.All-wavelength ultraviolet scanning results illustrate that the purity rate of LTA with anion-exchange chromatography TX114 is higher,and experiments show that LTA has good anti-bacterial activity and TX114 method is more effective.
出处 《长春工业大学学报》 CAS 2009年第4期447-450,共4页 Journal of Changchun University of Technology
基金 吉林省科技厅计划基金资助项目(20050403-4)
关键词 脂磷壁酸 冷酚法 抑菌活性 Lipoteichoic acid(LTA) cold phenol method anti-bacterial activity
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  • 1黄传富,谭光林.急性风湿热临床表现的变迁(附60例分析)[J].华西医学,1996,11(1):56-58. 被引量:1
  • 2王晶瑞,王承学.BP神经网络在液相传质系数中的应用[J].长春工业大学学报,2006,27(4):283-285. 被引量:3
  • 3Morath S, Stadelmaier A, Geyer A, et al. Synthetic lipoteichoic acid from Staphylococcus aureus is a potent stimulus of cytokine release [J]. J Exp Med, 2002, 195 (12): 1 635-1640.
  • 4Levels JH, Abraham PR, van Barreveld EP, et al. Distribution and kinetics of lipoprotein-bound lipoteichoic acid [J].Infect Immun, 2003, 71 (6): 3 280-3 284.
  • 5Triantafilou K, Triantafilou M, Dedrick RL. Interactions of bacterial lipopolysaccharide and peptidoglycan with a 70 kDa and an 80 kDa protein on the cell surface of CD14+ and CD14- cells [J]. Hum Immunol, 2001, 62 (1): 50-63.
  • 6O'Neill LA, Dunne A, Edjeback M, et al . Mal and MyD88: adapter proteins involved in signal transduction by Toll-like receptors [J]. J Endotoxin Res, 2003, 9 (1):55 - 59.
  • 7van Oosten M, van Amersfoort ES, van Berkel TJ, et al.Scavenger receptor-like receptors for the binding of lipopolysaccharide and lipoteichoic acid to liver endothelial and Kupffer cells [J]. J Endotoxin Res, 2001, 7 (5): 381-384.
  • 8Leemans JC, Heikens M, van Kessel KP, et al. Lipoteichoic acid and peptidoglycan from Staphylococcus aureus synergistically induce neutrophil influx into the lungs of mice [ J]. Clin Diagn Lab Immunol, 2003, 10 (5): 950-953.
  • 9Okamoto M, Ohe G, Furuichi S, et al. Enhancement of antitumor immunity by lipoteichoic acid-related molecule isolated from OK-432, a streptococcal agent, in athymic nude mice bearing human salivary adenocarcinoma: role of natural killer cells [J]. Anticancer Res, 2002, 22 (6A): 3 229 - 3 239.
  • 10Lotz S, Aga E, Wilde I, et al. Highly purified lipoteichoic acid activates neutrophil granulocytes and delays their spontaneous apoptosis via CD14 and TLR2 [ J]. J Leukoc Biol,2004, 75 (3): 467-477.

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