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氟比洛芬酯并瑞芬太尼等复合快通道麻醉在高龄患者腹部手术中的应用 被引量:3

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摘要 目的:观察预注氟比洛芬酯并瑞芬太尼等复合快通道麻醉在高龄患者腹部手术中的安全性和有效性。方法:将56例上腹部手术的高龄患者分为A、B两组,每组各28例,均采用全身麻醉。A组术前30min静注氟比洛芬酯50mg。两组术中均采用瑞芬太尼、双异丙酚、卡肌宁、七氟醚等静脉复合麻醉。观察两组患者麻醉前、插管前后、切皮后、睁眼时的BP、HR,清醒拔管的时间,术中是否知晓,术后2、4、8、12、24h的VAS评分,术后24h需用哌替啶的人数及开始使用时间以及术后不良反应。结果:两组麻醉诱导后BP、HR均明显降低,与麻醉前比较差异有统计学意义(P<0.05),B组手术结束睁眼时HR明显增快(P<0.05)。B组术后2、4、8、12hVAS评分比A组高(P<0.05)。A组需用镇痛药的人数(9/28)明显少于B组(27/28)(P<0.05),时间明显迟于B组(P<0.01)。两组苏醒快速完全,无术中知晓,恶心、呕吐、呼吸抑制等并发症少。结论:氟比洛芬酯术前预注,并用瑞芬太尼、双异丙酚、卡肌宁、七氟醚等快通道麻醉生理干扰小,镇痛佳,苏醒迅速完全,是适合老年患者上腹部手术的安全、有效、的麻醉方法。
出处 《交通医学》 2009年第4期415-417,共3页 Medical Journal of Communications
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