正元生白散联合化疗治疗晚期乳腺癌

Clinical Observation on Treatment of Breast Cancer in Advanced Stage with ZhengYuanShengBai Podwer Combined with Chemotherapy

目的探讨正元生白散联合化疗治疗晚期乳腺癌的临床疗效及安全性。方法将90例晚期乳腺癌患随机分为两组，其中治疗组50例，对照组40例；两组均行长春瑞滨加吡柔比星化疗两个疗程，治疗组同时使用中药正元生白散，于化疗第1天及最后1天采血、检查患者血象、肝肾功能及一般情况并记录。结果治疗组近期疗效与对照组无明显差异；治疗组生活质量明显高于对照组，毒性反应小于对照组。结论正元生白散联合化疗治疗晚期乳腺癌能提高生活质量，减少化疗的相关毒性反应。

Objective To observe the effects and safety of ZhengYuanShengBai powder combined with chemotherapy treating breast cancer in advanced stage. Methods 90 patients with breast cancer in advanced stage hospitalized from Oct. 2005 to Oct. 2007 were randomly recruited into a treatment group （50 cases） and a control group （40 cases）. Both groups were treated with vinorelbine and priarubicin for two courses of treatment. The treatment group was additionally administrated with ZhengYuanShengBai powder for treatment. Blood sample was drew at the first and last day of chemotherapy to examine the hemogram and liver and renal function. Results There was no obvious difference between the two group in terms of short period effects. While the quality of life and toxic reaction in the treatment group were obvious better than the control group. Conclusion ZhengYuanShengBai powder can improve the quality of life and reduce side effects of chemotherapy in patients of advanced breast cancer.