摘要
心房颤动是临床最常见的心律失常之一,现今研究支持其发病机制是多因素的。近年来研究表明,除电重构以外,结构重构在心房颤动的发生及发展过程中也起了至关重要的作用。本文综合近几年研究进展,从细胞内钙超载,心房壁牵张,纤维化变性以及炎症因素4个方面对心房颤动中结构重构的几种主要机制予以综述。
Atrial fibrillation is one of the most common cardiac arrhythmia in clinical.Researches supported the pathogenesis including multiple factors.Studies of recent years indicated that electrical remodeling,as well as the structural remodeling,play a significant role in the development of atrial fibrillation.The artical reviewed recent advances about structural remodeling in atrial fibrillation from aspects of intracellular calcium overload,atrial wall stretch,fibrosis and inflammation.
出处
《医学综述》
2009年第20期3101-3104,共4页
Medical Recapitulate
基金
昆明医学院研究生创新基金(KM2008L35)
关键词
心房颤动
结构重构
Atrial fibrillation
Structural remodeling
