N-(4-氯-2-硝基苯基)-2-甲基丙烯酰胺的合成

Synthesis of N-(4-chloro-2-nitro Phenyl)-2-methacrylamide

以对氯磷硝基苯胺、甲基丙烯酸为原料,二甲苯为溶剂,P2O5为催化剂合成得到N-(4-氯-2-硝基苯基)-2-甲基丙烯酰胺,产率为62%。研究了反应物的物质的量比、催化剂用量和反应时间对合成N-(4-氯-2-硝基苯基)-2-甲基丙烯酰胺的影响,得到最佳反应条件。并对产品进行了IR和NMR的结构鉴定。

N-（4-chloro-2-nitro Phenyl）-2-methacrylamide was synthesized by reaction of 4-chloro-2- nitroaniline and methyl acrylic acid with xylene as solvent,phosphorus pentoxide as catalyst,the productive capacity was 62%.The effects of reactant ratio,catalyst,time were studied in this paper.The structure of product was confirmed by IR and NMR.