检后支气管舒张试验对咳嗽变异性哮喘的诊断价值

The diagnostic value of bronchodilation test after bronchial provocation test (BAT) on cough variant asthma

目的探讨检后支气管扩张试验对咳嗽变异性哮喘(CVA)的诊断价值。方法选取48例气道反应性增高的慢性咳嗽患者,采用两种方法进行诊断:一种是检后支气管舒张试验,另一种盐酸丙卡特罗诊断试验。判断检后支气管舒张试验的诊断价值。结果48例患者接受检后支气管舒张试验,FEV1增加3%～46%,平均22.8%±8.8%。盐酸丙卡特罗诊断试验显示,48例患者中,阳性38例,占受检人数的79.2%,阴性10例,占20.8%。检后支气管舒张试验诊断CVA的灵敏度为84.2%,特异度80%,阳性预测值94.1%,阴性预测值57.1%。诊断的正确率为83.3%。结论检后支气管舒张试验可以缩短诊断时间,对CVA具有较好的诊断价值。

Objective To investigate the diagnostic value of bronchodilation test after Bronchial provocation test （BAT） on cough variant asthma （CVA）. Methods 48 cases with airway hyperreactivity were diagnosed as CVA by two different methods. One was a new method named BAT, and the other was a standard method named procaterol diagnostic test （PDT）. The two methods were compared in order to explore the diagnostic role of BAT. Results Among the 48 cases, 38 cases got positive results by PDT. The sensitivity and specificity of BAT calculated from PDT were 84.2%, 80%, respectively. The positive predictive value and the negative predictive value of BAT calculated from PDT were 94. 1%, 57. 1%, respectively. Conclusion BAT has a good diagnostic value for the diagnosis of CVA and can save time in the diagnosis of CVA compared with PDT.