佛山地区肠球菌属的检测及耐药性分析

The detection of enterococcus and analysis of antibiotic resistance in Foshan area

目的探讨佛山地区肠球菌属感染的流行状况,动态观察肠球菌属耐药特性变迁特点,指导临床医生合理、有效地使用抗生素。方法对我院2006-2008年临床送检标本进行常规微生物培养和药敏试验。结果2006-2008年共检出肠球菌属细菌558株,菌株以粪肠球菌为主,其次为屎肠球菌;肠球菌属在各标本中的分布以分泌物为主,痰液标本中肠球菌属的比例逐年增加;肠球菌属对环丙沙星、左氧氟沙星和喹奴普汀-达福普汀有较高耐药性,对万古霉素和替考拉宁仍有较高敏感性。结论3年来在细菌种类和耐药方面肠球菌属均发生了较大变化,不同种类的细菌其耐药性差异很大,因此临床应根据药敏试验结果选择敏感抗菌药,以提高疗效,减少医院感染。

Objective To study the epidemic tendency and antibiotics-resistance of enterococcus spp so as to guide an appropriate use of antibiotics in clinic.Methods To culture conventional microbiological and take sensitivity tests from Foshan Hospital of traditional Chinese medicine during 2006 to 2008.Results Total of 558 strains of enterococcus spp were isolated from 2006 to2008. The main strain of enterococci was enterococcus faecalis.E.faecium was the second one. The isolation rate of enterococci, which were the highest in secretion specimens, was increasing in sputum specimens year by year.The drug-resistance rate of enterococci to Ciprofloxacin,Levofloxacin and Quinupristin/Dalfopristin was high, but it was still sensitive to vancomycin and teicoplanin.Conclusions Great changes have taken place in the bacterial distribution and drug-resistance of isolated enterococci, and the drug-resistance of strains of enterococci differed greatly during the last 3 years.To insure effective treatment and decrease the infection of enterococci in hospital, the antibiotics sensitive to enterococci should been used on the basis of drugresistance test when the infection of enterocoeci was treated Clinically.