偏振反射光谱在生物医学光子学中的应用

Application of Polarized Reflectance Spectroscopy in Biomedical Photonics

偏振反射光谱是近年来生物医学光子学中发展迅速的一种新型诊断组织信息技术,能对生物组织微观结构组成进行快捷准确的探测,具有强偏振敏感、非侵入、低成本和快速等特性,在肿瘤的早期诊断和在体生物组织的上皮黏膜检测研究等方面具有重要的应用价值。综述了偏振反射光谱技术的基本原理和测量装置及其在肿瘤的早期诊断和在体生物组织上皮黏膜的光检测等生物医学方面的研究。

Polarized reflectance spectroscopy is rapidly developed in biomedical photonics as a novel technique of diagnosing biological tissues in recent years, and it can rapidly and accurately detect the microstructure and component of biological tissues. For the characteristics of strong polarization sensitivity, low-cost, noninvasion and rapidness, the polarized reflectance spectroscopy has application value in the noninvasivel examination for the early tumor and in vivo detection for mucosal epithelium of biological tissue. The fundamental principles, measurement devices and investigation in the above field for the polarization reflectance spectroscopy are briefly summarized.