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GDP方案治疗复发性非霍奇金淋巴瘤27例 被引量:1

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摘要 目的观察吉西他滨(GEM)联合顺铂(DDP)、地塞米松(DXM)组成的GDP方案治疗复发性非霍奇金淋巴瘤(NHL)的近期疗效和患者不良反应。方法GEM1000mg/m^2,静脉滴注30min,第1、8天;DDP20mg/m^2,静脉滴注,第1天至第5天;DXM20mg/d,口服,第1天至第5天;21d为1个周期。2个周期后评价疗效,并随访疾病进展情况。结果27例患者中完全缓解(CR)4例,部分缓解(PR)12例,有效(CR+PR)率59_3%。肿瘤中位进展(TTP)时间4.5个月,1年生存率32.3%。不良反应主要为血液学毒性和恶心、呕吐。结论GEM作为化疗有效药物,可用于治疗NHL;GDP方案可作为治疗复发性NHL的有效挽救方案之一。
出处 《肿瘤研究与临床》 CAS 2009年第10期700-702,共3页 Cancer Research and Clinic
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