胎儿宫内窘迫、出生时窒息、血气分析与早产儿脑室周围-脑室内出血关系

Analysis on the relationship between fetal distress、birth asphyxia、 blood gas analysis and intraventricular hemorrhage of premature infants

目的研究胎儿宫内窘迫、出生时窒息、血气分析与早产儿脑室周围-脑室内出血的关系,并探讨其临床意义。方法收集2006年7月至2008年6月收入秦皇岛市妇幼保健院新生儿科的351例早产儿,根据有无脑室周围-脑室内出血分为观察组和对照组。结果①351例早产儿,179例脑室周围-脑室内出血的早产儿为观察组,其余为对照组。②观察组合并胎儿宫内窘迫者155例;③观察组中合并出生时窒息25例;④与早产儿脑室周围-脑室内出血关系密切的血气有PO2、PCO2、BE,经统计学分析有显著差异(P<0.01)。结论早产儿脑室周围-脑室内出血与胎儿宫内窘迫、出生时窒息、血气分析中提示的缺氧、高碳酸血症和酸中毒密切相关,对早产儿尤其是存在胎儿宫内窘迫和/或出生时窒息和/或血气分析异常早产儿常规行颅内B超检查很有必要。提高早产儿生存率及生活质量应从宫内做起。

Objective To study the chnical significance through analyzing the relationship between fetal distress.birth asphyxia.blood gas analysis and intraventficular hemorrhage of premature infants. Methods There were 351 premature infants collected from July 2006 to June 2008 who were divided into observation group with intraventricular hemorrhage and control group with no intraventricular hemorrhage. Results There were 179 infants with intraventricular hemorrhage, 25 examples with asphyxia and 155 examples with fetal distress in observation group among all 351 examples. There was close relationship between PO2, PCO2, BE in blood gas analysis and intraventricular hemorrhage of premature infant that the difference was significant （ P 〈 0. 01 ）. Conclusion Intraventricular hemorrhage of premature infants closely related to fetal distress, birth asphyxia, blood gas analysis that showed the hypoxiahypercapnia and acidosis. It was necessary to carry on encephalic ultrasound examination for premature infants conventionally. The survival rate and life quality should be enhanced through some examination from pregnancy.