摘要
目的:观察白花蛇舌草总黄酮体外对HepG-2肿瘤细胞增殖的抑制作用。方法:以HepG-2细胞为实验细胞株,观察白花蛇舌草中的总黄酮对HepG-2肿瘤细胞形态的影响;用流式细胞仪检测细胞的凋亡。结果:白花蛇舌草总黄酮对HepG-2肿瘤细胞形态有影响,抑制其生长并诱导HepG-2肿瘤细胞的调亡。结论:白花蛇舌草中的总黄酮通过诱导凋亡对人肝癌细胞HepG-2有抑制增殖作用。
Objectives: To observe the inhibiting effect of flavone from Oldenlandia diffusa(willd.) Roxb. on HepG-2 cell in vitro. Methods: The effect of cell growth inhibition was observed through the cell shape and apoptosis was assessed by flow cytometry. Results: The flavone from Oldenlandia diffusa(willd.)Roxb. inhibited HepG-2 cell growth and induce apoptosis. Conclusion: The flavone from Oldenlandia diffusa(willd.) Roxb. inhibit HepG-2 cell by induction of apoptosis.
出处
《抗感染药学》
2009年第3期179-181,共3页
Anti-infection Pharmacy