慢性阻塞性肺疾病呼出气冷凝液中的生物标记物及其意义

Biomarkers and significance in exhaled breath condensate of chronic obstructive pulmonary disease

呼出气冷凝液（exhaled breath condensate，EBC）是一种无创研究气道内衬液成分的方法，也为评估肺部炎症提供可能。目前普遍认为，慢性阻塞性肺疾病（chronic obstructive pulmonary disease，COPD）是以气道、肺实质和肺血管的慢性炎症为特征的疾病。通过对COPD患者EBC的收集和检测，可实现对气道炎症的实时、无创、简单、重复的监测。

Analysis of exhaled breath condensate（EBC） is a noninvasive method for studying the composition of airway lining fluid and has the potential for assessing lung inflammation. It is well known that chronic obstructive pulmonary disease（COPD） is characteristic of chronic inflammation of the airway, lung parenchyma and pulmonary blood vessels. Through the collecting and testing EBC of COPD patients, real- time, non-invasive, simple and repetitive monitoring can be realized on airway inflammation.