血浆同型半胱氨酸与阻塞性睡眠呼吸暂停低通气综合征并心血管疾病的研究进展
Research progress on serum homocysteine and obstructive sleep apnca-hypopnea syndrome with cardiovascular disease
摘要
目前有研究证实高同型半胱氨酸血症及阻塞性睡眠呼吸暂停低通气综合征均为心血管疾病的独立危险因素,但同型半胱氨酸与阻塞性睡眠呼吸暂停低通气综合征间的关系尚不清楚。本文简要概述三者间相关的研究进展。
Many studies show that hyperhomocysteinemia and obstructive sleep apnea-hypopnea syndrome(OSAHS) are both independent risk factors of cardiovascular disease. But the further relationship between homocysteine and OSAHS is unknown. This article summarizes the current related studies.
出处
《国际呼吸杂志》
2009年第19期1201-1203,共3页
International Journal of Respiration
参考文献18
-
1McCully KS. Vascular pathology of homocysteinemia: implications for the pathogenesis of arteriosclerosis. Am J Pathol, 1969,56 : 111-128.
-
2Ubbink JB, Vermaak WJ, Delport R, et al. Effective homocysteine metabolism may protect South African blacks against coronary heart disease. Am J Clin Nutr, 1995,62 : 802- 808.
-
3Chobanian AV, Bakris GL, Black HR, et al. The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: the J NC 7 report. JAMA, 2003,289 : 2560-2572.
-
4Usui K, Bradlev TD, Spaak J, et al. Inhibition of awake sympathetic nerve activity of heart failure patients with obstructive sleep apnea by nocturnal continuous positive airway pressure. J Am Coll Cardiol, 2005,45 : 2008-2011.
-
5Takama N, Kurabayashi M. Possibility of close relationship between sleep disorder breathing and acute coronary syndrome. J Cardiol, 2007,49 : 171-177.
-
6Lavie L, Kraiezi H, Hefetz A, et al. Plasma vascular endothelial growth factor in sleep apnea syndrome: effects of nasal continuous positive air pressure treatment. Am J Respir Crit Care Med,2002,165 : 1624-1628.
-
7Wilcken DE,Wilcken B. The pathogenesis of coronary artery disease. A possible role for methionine metabolism. J Clin Invest, 1976,57 : 1079-1082.
-
8Harker LA,Ross R, Slichter SJ, et al. Homocysteine-induced arteriosclerosis. The role of endothelial cell injury and platelet response in its genesis. J Clin Invest, 1976,58: 731-741.
-
9Lang D, Kredan MB, Moat SJ, et al. Homocysteine-induced inhibition of endothelium-dependent relaxation in rabbit aorta:role for superoxide anions. Arterioscler Thromb Vase Biol, 2000,20 : 422-427.
-
10Boushey CJ, Beresford SA, Omenn GS, et al. A quantitative assessment of plasma homocysteine as a risk factor for vascular disease: probable benefits of in creasing folic acid intakes. JAMA, 1995,274 : 1049-1057.
二级参考文献15
-
1张文莉,王士雯,徐斌,黄丽洁,苟鹏,高磊,李泱,高伟.中国小型猪阻塞型睡眠呼吸暂停模型的建立[J].中国比较医学杂志,2004,14(5):286-289. 被引量:22
-
2[1]Szabóová E,Tomori Z,Donic V,et al.Sleep apnoea inducing hypoxemia is associated with early signs of carotid atherosclerosis in males.Respir Physiol Neurobiol,2007,155:121-127.
-
3[2]Saletu M,Nosiska D,Kapfhammer G,et al.Structural and serum surrogate markers of cerebrovascular disease in obstructive sleep apnea(OSA):association of mild OSA with early atherosclerosis.J Neurol,2006,253:746-752.
-
4[3]Rasouli ML,Nasir K,Blumenthal RS,et al.Plasma homocysteine predicts progression of atherosclerosis.Atherosclerosis,2005,181:159-165.
-
5[4]Gupa M,Sharma P,Garg G,et al.Plasma homocysteine:an independent or an interactive risk factor for coronary artery disease.Clin Chim Acta,2005,352:121-125.
-
6[5]Graham IM,Daly EL,Refsum HM,et al.Plasma homocysteine as a risk factor for vascular disease:the European concerted action project.JAMA,1997,277:1775-1781.
-
7[6]Kokturk O,Ciftci TU,Mollarecep E,et al.Serum homocysteine levels and cardiovascular morbidity in obstructive sleep apnea syndrome.Respir Med,2006,100:536-541.
-
8[7]Kumor M,Rubinsztajn R,Byskiniewicz K,et al.Serum concentration of homocysteine and the risk of atherosclerosis in patients with obstructive sleep apnea syndrome.Pneumonol Alergol Pol,2006,74:117-121.
-
9[9]Loscalzo J.The oxidant stress of hyperhomocyteinemia.J Clin Invest,1996,98:5-7.
-
10[10]Upchureh GR,Welch GN,Fabian AJ,et al.Homocysteine decreases bioavailable nitric oxide by a mechanism involving glutathione peroxidase.J Biol Chem,1997,272:17012-17017.
共引文献3
-
1张宏英,林其昌,陈力舟,李树奇,赵建铭,陈华.血浆同型半胱氨酸在阻塞性睡眠呼吸暂停低通气综合征并心血管疾病中的意义探讨[J].国际呼吸杂志,2010,30(13):776-779. 被引量:3
-
2段付军,徐先荣,张丹,刘登高,张永昕,陈智威,肖承祥.MTHFRC677T基因多态性与歼击机飞行员血浆总同型半胱氨酸关系的调查分析[J].空军医学杂志,2022,38(2):93-95. 被引量:1
-
3张宏英,张龙华,陈红霞.肥胖阻塞性睡眠呼吸暂停低通气综合征血浆同型半胱氨酸水平的研究[J].中外医学研究,2019,17(8):1-3. 被引量:2
-
1张宏英,林其昌,陈力舟,李树奇,赵建铭,陈华.血浆同型半胱氨酸在阻塞性睡眠呼吸暂停低通气综合征并心血管疾病中的意义探讨[J].国际呼吸杂志,2010,30(13):776-779. 被引量:3
-
2赵爱社,任丽琴,武学勤.良性阵发性位置性眩晕308例诊治体会[J].山西职工医学院学报,2015,25(5):47-49.
-
3王霞,孙喜琢,姚福梅,王久国.阻塞型睡眠呼吸暂停综合征患者血浆同型半胱氨酸的变化[J].中华高血压杂志,2008,16(3):253-256. 被引量:5
-
4梁云娴.阻塞性睡眠呼吸暂停综合征血浆Hcy水平及相关危险因素分析[J].现代医院,2014,14(2):70-71. 被引量:3
-
5王丛,王春燕,马琳琳,张奕,赵立明,高春锦,侯晓敏.突发性聋患者全身伴发疾病的临床分析[J].临床耳鼻咽喉头颈外科杂志,2017,31(2):85-87. 被引量:7
-
6张应忠.老年患者血管性痴呆发病相关危险因素调查分析[J].中国医院统计,2015,0(4):251-253. 被引量:4
-
7田文静,王彦辉,孙祖真,杨燕.鲁西南地区青年大脑中动脉狭窄的危险因素[J].中国医学工程,2014,22(2):97-97.
-
8张文莉,王士雯,赵玉生,高磊,徐斌,刘谟焓,高伟,李泱,朱庆磊.实验性阻塞型睡眠呼吸暂停综合征小型猪的血浆同型半胱氨酸水平[J].中华老年多器官疾病杂志,2007,6(6):414-417. 被引量:4
-
9董彬,赵雅宁,李建民.血浆同型半胱氨酸与老年阻塞性睡眠呼吸暂停低通气综合征合并高血压性脑出血认知功能的相关性[J].中国老年学杂志,2016,36(21):5380-5383. 被引量:6
-
10辛凤,袁永一,戴朴.V-ATPase与耳聋相关的研究进展[J].中华耳科学杂志,2014,12(1):77-80. 被引量:1