孕前TORCH筛查8395例分析

Analysis on 8395 Cases of Pre-pregnancy TORCH Screening

目的了解准父母孕前微生物感染状况,为制定出生缺陷干预措施提供依据。方法对8395名孕前准父母采血进行TORCH综合征的筛查,结果进行回顾性统计分析。结果常规4项筛查(CMV、RV、HBV、Tox)IgM阳性1008人,阳性率12.00%;单项阳性735人,阳性率8.76%;合并阳性273人,阳性率3.25%。结论孕前TORCH感染阳性率较低,且父系传给子代的机会极少,母亲感染并不意味胎儿感染,故对准父母进行TORCH筛查的必要性需慎重考虑。

[ Objective]To study the microorganism infection status during pre-pregnancy, provide evidence for making interventions of birth defect. [Methods]TORCH syndrome screening were carried out in 8395 couples before pregnancy by blood collecting, the results were analyzed retrospectively. [ Results ] The conventional screening （CMV, RV, HBV and Tox） IgM positive were detected in 1008 cases, and the positive rate was 12.00 %. 735 （ 8.76% ） cases were single positive, and 273 { 3.25% ） cases were com- bined positive. [ Conclusion] The positive rate of pre-pregnancy TORCH infection was relatively low, and the infection probability from paternal line pass to offspring was very little. Mother infected did not mean fetus infected too, so the necessity of TORCH screening among couples before pregnancy should be considered carefully.