脑单发低密度病灶的CT与病理对照研究

Correlative Study of CT and Pathology on Single Lesions of Low-Density in Brain

目的：阐明脑单发低密度病灶的实质．材料与方法：收集26例进行CT与病理对照研究。结果：该类病灶以低级别胶质瘤最多见，还可见于病毒性脑炎、皮样囊肿及脑软化等。低密度改变与组织学上细胞密度低、细胞核染色质不丰富及间质内空泡多一致。结论：低密度的实质是DNA含量低及水含量高，不强化与血供不丰及血脑屏障完整有关，预后多较好。

Purpese: To demonstrate the nature of single low-density non-enhancing lesions in brain on CT scan. -Materials and Methods: Correlative study of CT and pathology was made in 26 cases. Results: Low-grade glioma was found at the most frequency, and viral encephalitis, dermoid cyst and encephalodialysis at less frequency. The low density areas on CT scan were consistent with the low density of cells, light dyed nuclei and moregnicro-bubbles in histology' Conclusion: The low density could be interpreted as less DNA and more water in the lesions. Less vessels and complet blood-brain barrier were responsible for the non-enhancement. Most of the cases coould have favorable prognosis.