肝硬化患者血清白蛋白、胆碱酯酶与肝性脑病的关系研究

To research the relationship of blood albumin, Chocinesterase and hepatic encephalopathy of hepatic cirrhosis paitents

目的探讨肝硬化患者血清白蛋白、胆碱酯酶与肝性脑病的关系。方法对79例肝硬化患者血清白蛋白、胆碱酯酶进行测定，统计不同等级肝功能患者肝性脑病的发病率。结果随着肝功能的恶化，肝性脑病发病率呈上升趋势；肝硬化患者白蛋白和胆碱酯酶与对照组比较，差别有统计学意义（P〈0．05）；对于ChildA与ChildB级肝功能肝硬化患者而言，肝性脑病的发病率其差别具有统计学意义（P〈0．05）；而对于ChildB和ChildC级肝功能患者而言，肝性脑病的发病率其差别无统计学意义（P〉0．05）。结论随着白蛋白和胆碱酯酶的降低，肝性脑病发病率呈上升趋势。在临床工作中，应根据不同肝功能等级决定白蛋白的补充。

Objective To study the relationship between the albumin, acetylcholine esterase and the hepatic encephalopathy of hepatic cirrhosis patients. Methods The albumin and acetylcholine esterase has been deter mined of 79 hepatic cirrhosis patients, then calculating the disease incidence of hepatic encephalopathy. Results The hepatic encephalopathy incidence upgrades following liver function gets worse;There is statistical difference between the hepatic cirrhosis patients and control group about albu min and acetylcholine esterase （P 〈 0.05） ; As for the hepatic cirrhosis patients whose liver function are Child A and Child B, the hepatic encephalopathy incidence has statistical difference （ P 〈 0.05） ; But for the hepatic cirrhosis patients whose liver function are Child B and Child C, the hepatic encephalopathy incidence has no statistical difference （P 〉 0.05）. Conclusion The hepatic encephalopathy incidence upgrades following albu min and acetylcholine esterase decrease. In clinical work, wed better base on the different liver function to fill up the albumin.