C肽胰岛素在糖尿病诊治中的作用

Role of C - peptide of insulin in the diagnosis and treatment of diabetes

目的通过对血清中C肽和胰岛素含量测定结果来了解2型糖尿病中糖代谢和胰岛8细胞功能。方法对80例2型糖尿病患者及84例正常人馒头餐代谢试验用美国[DPC]化学发光测定仪检测C肽和胰岛素。结果2型糖尿病空腹C肽和胰岛素高于正常人（P〈0．05），餐后2h才达到高峰（餐后1h对照组出现峰值），餐后3h仍不能恢复至正常水平。结论试验组患者胰岛功能存在轻度障碍，测定血C肽可以准确反映胰岛分泌功能。

Objective C - peptide and serum insulin deter mination to know the outcome of type 2 diabetes and glucose metabolism in islet β- cell function. Methods 80 cases of patients with type 2 diabetes and 84 cases of normal metabolism test meal with steamed the United States[ DPC ] Detect chemilu minescent detector C -peptide and insulin. Results Type 2 diabetes fasting C -peptide and insulin than normal （ P 〈 0.05 ）, postprandial 2 h to reach the peak （ 1 h postprandial peak value in control group）, 3 h after meal can not restore to normal levels. Conclusion Test islet function in patients with mild obstacles exist; blood C - peptide can be deter mined accurately reflect insulin secretion.