红外光谱宏观指纹鉴定法与中药的质量控制

Macro-fingerprint infrared spectroscopic identification method and the quality control of traditional Chinese medicines

本文简述基于红外光谱的复杂混合物体系整体分析方法,即针对中药质控的"红外光谱宏观指纹鉴定法"。综述使用红外光谱对生药材、中药制剂的鉴定识别,对中药炮制过程以及对特定组分的定量分析研究等。该方法遵循中药理论中重视整体用药的原则,无需对待测样品进行分离提取,不丧失药物的原本性质和配伍性,提供一种有效而简易的中药质量控制方法。

An integrated analysis method via Infrared spectroscopy for complex materials, namely the macro-fingerprint infrared spectroscopic identification method, is introduced in this article. Major applications of the method are face to the quality control of traditional Chinese medicines （TCM）. Fast and non-destructive identification of the crude drugs and their producing area are reviewed for the first time. Analysis and evaluation the quality of preparation of TCM, including the preparing procedure of medicines and the determination of types and quantity of the auxiliary materials added in the TCM products are also reviewed. The method follows the holistic principles emphasized by Chinese Medicine. Without separation and extraction, the method does not lose originality and compatibility of TCM during analysis. Obviously, it is the means or method. simplest, quick, convenient and non-separated detective