宫颈癌新辅助化疗临床研究现状

Clinical Researches of Neoadjuvant Chemotherapy for Cervical Cancer

新辅助化疗是指在局部治疗(手术或放疗)前给予的全身化疗。近二十余年来国内外学者对宫颈癌新辅助化疗联合手术或放疗的治疗模式进行了一些探索,取得一定经验。但新辅助化疗在宫颈癌治疗中的地位仍未明确,且对其化疗方案选择目前无统一认识。对新辅助化疗在宫颈癌治疗方面的最新进展、多种新辅助化疗方案应用于宫颈癌的疗效及其发展趋势做综述。

Neoadjuvant chemotherapy refers to systemic chemotherapy given to patients before local treatment （surgery or radiotherapy ）. Scholars from both China and abroad have explored the modality therapy for neoadjuvant chemotherapy combined with surgery or radiotherapy on cervical cancer over the last two decades and they have learned certain experiences in this area. But the status of this therapy is not clear yet and there is no consensus on how to choose its appropriate chemotherapy protocol. The latest therapeutic progress of neoadjuvant chemotherapy, the effect of various regimens, and their development trends now are being reviewed.