无氧阈在慢性阻塞性肺疾病患者康复治疗中的应用

Clinical Significance of Anaerobic ThreshOld (AT) for Pulmonary Rehabilitation in Patients with Chronic Obstructive Pulmonary Disease(COPD)

目的:观察无氧阂在慢性阻垂柱肺疾病(COPD)患者康复治疗中的应用价值。方法:选择30例COPD稳定期患者用运动负荷递增方法(每隔2分钟增25w)进行运动试验测得无氧阂(AT),制定个体运动处方,进行为期8周的康复训练,康复治疗前后测患者的6min步行距离(6MWD)、生存质量、肺动脉收缩压及静态肺功能。结果:(1)24例患者完成了8周的康复训练治疗,治疗后平均6MWD从378M增加到450M(P<0.001)。(2)生存质量问卷(CRQ)的改善差异有显著性意义。(3)肺功能收缩压从19.28mmHg降至15.47mmHg(P<0r05)。(4)FEVl虽然从1.16L增加至1.2lL,比较差异无显著性意义(P>0.05)。结论:以无氧阈为标准制定个体运动处方进行康复训练治疗能显著提高COPD患者的运动能力,改善其生存质量,避免运动性低氧血症及运动性肺动脉高压的发生。

Objective：TO observe the clinical significance of AT for pulmonary rehabilitation in patients with COPD, so as to explore the exerelse Intenshy in pulmonary rehabi 士itation. Methods.. In 30 patientswithCOPDaprogressively incremental （25Weach twominute） exercisetestwas undergon. And AT was measured. It may be described and measuredrehabl 上RatiOn therapy byAT. ThepatientswithCOPD tockpart ina 8weekspulmonary rehabi tation. The outcome measurement included 6MWD, CRQ, pulmonary arterial systolic pressure, and static pulmonary function. Results： After 8 weeks exercise rehabilitation, 6MWD Of pat ents with COPDwas Increased from 378meters to 450meters（P〈0. 001）. The improvements of CRQ reached to statistically and clinically significant improvements. Pulmonaryarterial systolic pressure of patients decreased from 19. 28mmHgto 15. 47mmHg（P〈0. 05）. Although FEVI of patients increased from 1. 16L to1.21L, there was no significant difference（P〉0. 05）. Conclusion：described andmeasured rehabilitation therapy byAT. The progra the exercise eapacty and quality of life in patients with hypoxia and exercise--induced pulmonary arteria hypertension.