丁酸钠对肉仔鸡生产性能及免疫功能的影响

Effects of Sodium Butyrate on Growth Performance and Immune Function in Broilers

试验选择体重基本一致的健康AA肉仔鸡300羽,随机分成5组:Ⅰ组(对照组)、Ⅱ组(250mg/kg丁酸钠)、Ⅲ组(500 mg/kg丁酸钠)、Ⅳ组(1 000 mg/kg丁酸钠)、Ⅴ组(40 mg/kg杆菌肽),每组6个重复,每个重复10羽,试验期21 d。试验结果表明:(1)14日龄采食量、增重、体重显著高于对照组(P<0.05),21日龄有增加趋势;14日龄料重比显著降低(P<0.05),21日龄有降低趋势。(2)14日龄和21日龄脾脏指数、胸腺指数、法氏囊指数有提高的趋势。(3)14日龄十二指肠上皮内淋巴细胞(IEL)数量显著高于对照组(P<0.05);21日龄十二指肠、空肠、回肠IEL数量均显著高于对照组(P<0.05)。(4)14日龄十二指肠及回肠杯状细胞(GC)数量均显著高于对照组(P<0.05);21日龄空肠及回肠GC数量显著高于对照组(P<0.05)。

Three hundred day-old AA broiler chickens were allocated randomly into five groups with six replicates each ten birds.The birds were fed between 1 to 21 d of age.Five groups were fed separately with basal diet（control）,diets supplemented with sodium butyrate（SB） at level of 250,500,1000 mg/kg,and diet supplemented with bacitracin at level of 40 mg/kg.Results： ⑴ Compared with the control group,the feed intake,body weight gain and body weight at the age of 14 d for groups fed diets with SB or bacitracin supplementation significantly increase （P 〈0. 05 = 0. 05 ）, and the feed conversion ratio significantly decrease （ P 〈 0. 05 = 0. 05 ）. Feed intake, body weight gain and body weight have an increasing trend at the age of 21 d, while feed conversion ratio has a decreasing trend. （2） The indexes of spleen, thymus and bursa of groups fed diets with SB or bacitracin supplementation are higher than that of control group at the age of 14 d and 21 d. （3） The intraepithelial lymphocytes number of duodenum, jejunum and ileum increase compared with control group at the age of 21 d, and at the age of 14 d the intraepithelial lymphocytes number of duodenum significantly increases （ P 〈 0. 05 = 0. 05 ）. （4） Compared with control group, the goblet cell number of duodenum and ileum significantly increase （P 〈0. 05 = 0. 05 ） at the age of 14d ; at the age of 21 d the goblet cell number of duodenum has a increasing trend, and the goblet cell number of jejunum and ileum significantly increase （P 〈0. 05 = 0. 05 ） compared with control group.