摘要
目的了解初诊2型糖尿病并代谢综合征患者血清visfatin和脂联素水平的变化,及其与各组份的相关性。方法采用酶联免疫法测定正常对照组、2型糖尿病组和2型糖尿病并代谢综合征组visfatin、脂联素水平,并分析visfatin、脂联素水平与其他指标的相关性。结果各组中visfatin、脂联素水平无明显变化,visfatin与甘油三酯正相关(r=0.199,P<0.05);脂联素与BMI(r=0.239,P<0.05)、胰岛素(r=0.202,P<0.05)、胰岛素抵抗指数(r=0.238,P<0.05)、年龄正相关(r=0.208,P<0.05)。结论2型糖尿病并代谢综合征患者血清visfatin和脂联素水平无明显变化,visfatin和脂联素在代谢性疾病中的作用有待进一步研究。
Objective To investigate the change of visfatin and adipanectin levels in newly-diagnosed metabolic syndrome in type 2 diabetic patients and the relationship with other factors. Methods Visfatin and adiponeetin were measured by enzyme-linked immunoassay in patiens with type 2 diabetes and metabolic syndrome in type 2 diabetes ,and controls. The relationship of the levels of visfatin and adiponectin with other factors was analyzed. Results The levels of serum visfatin and adiponeetin showed no difference among the groups. Visfatin was positively associated with triglyceride,and adiponectin was positively associated with BMI,insulin, HOMA-IR and age. Conclusion The levels of serum visfatin and adiponectin show no change in metabolic syndrome in type 2 diabetic patienls,the role of visfatin and adiponectin in metabolic disease needs to be further investigated.
出处
《中国现代医生》
2009年第30期1-3,共3页
China Modern Doctor
