期刊文献+

遗传药理学的基本内容和研究进展 被引量:1

下载PDF
导出
摘要 本文主要介绍了遗传药理学的基本内容、研究历程和意义,以及目前主要的研究进展,旨在为药学工作者了解遗传药理学相关内容提供帮助。遗传药理学是当前医药领域的热点内容,以遗传药理学为基础的个体化治疗将是未来医学的重要发展方向。
出处 《中国执业药师》 CAS 2009年第10期3-9,共7页 China Licensed Pharmacist
  • 相关文献

参考文献5

二级参考文献62

  • 1李健,文思远,王睿,陈昆,方翼,裴斐,王升启.细胞色素P450CYP2C9基因多态性对甲苯磺丁脲代谢动力学的影响[J].药学学报,2005,40(8):695-699. 被引量:22
  • 2EFFERTH T,VOLM M.Pharmacogenetics for individualized canc er chemotherapy[J].Pharmacol Ther,2005,107:155-176.
  • 3VIRGILE G,MANUELA D,FRANCOIS B,etal.MRP 1,-3 and 5 protein expression in non-small cell carcinomas and surgery after adjuvant chemotherapy[J].Lung Cancer,2005,49 (s2):S149.
  • 4HIRANO T,KATO H,MAEDA M,etal.Identification of postoperative adjuvant chemotherapy responders in non-small cell lung cancer by novel biomarker[J].Int J Cancer,2005,117 (3):460-468.
  • 5HITRE E,BUDAI B,AKLEFF V,et al.Influence of thymidylate synthase gene polymorphisms on the survival of colorectal cancer patients receiving adjuvant 5-fluorouracil[J].Pharma cogenet Genomics,2005,15 (10):723-730.
  • 6INOUE K,TAKAO M,WATANABE F,et al.Role of dihydropyrimidine dehydrogenase inhibitory fluoropyrimidine against non-small cell lung cancer-in correlation with the tumoral expression of thymidylate synthase and dihydropyrimidine dehydrogenase[J].Lung Cancer,2005,49:47-54.
  • 7XIE H G, PRASAD H C, KIM R B, et al. CYP2C9 allelic variants:ethnic distribution and functional significance [ J ]. Adv Drug Deliv Rev ,2002,54:1257-1270.
  • 8RETTIE A E, JONES J P. Clinical and toxicological relevance of CYP2C9: drug-drug interactions and pharmacogenetics [ J ].Annu Rev Pharmacol Toxicol,2005 ,45:477-494.
  • 9YASAR U, ELIASSON E, FORSLUND-BERGENGREN C, et al.The role of CYP2C9 genotype in the metabolism of diclofenac in vivo and in vitro[J]. Eur J Clin Pharmacol,2001, 57 (10 ) :729-735.
  • 10SHIMAMOTO J, IEIRI I, URAE A,et al. lack of differences in diclofenac (a substrate for CYP2C9) pharmacokinetics in healthy volunteers with respect to the single CYP2C9 * 3 allele[J]. Eur J Clin Pharmacol,2000, 56(1) :65-68.

共引文献19

同被引文献12

引证文献1

二级引证文献8

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部