急性肺栓塞30例临床分析

Clinical Analysis of 30 Patients with Acute Pulmonary Embolism

报告我院确诊的30例急性肺栓塞(APE)病人,其中合并深部静脉血栓(DVT)11例占36.7％,原有心肺血管疾病者12例占40％,提示DVT及心肺血管疾病是APE的重要易发危险因素。本病患者临床表现缺乏特异性,对可疑肺栓塞者建议进行放射性核素肺灌注扫描检查,该方法是APE很有价值的诊断手段。本组患者用肝素抗凝治疗14例,住院期间死亡1人,病死率为7.14％;非肝素治疗16例,死亡5人,病死率为31.25％,明显高于肝素治疗组(P<0.05)。显示急性期肝素抗凝治疗效果显著。

Thirty cases of acute pulmonary embolism(APE)were investigated,36.7% of them were concurrent with deep venous thrombus (DVT) and 40% had basal angiocardiopathy or angiopulmonopathy. It showed that DVT and the angiopathy of heart and lung were important risk factors for APE. The clinical manifestations had no specificity. It was advised that the radionuclide pulmonary perfusion scanning should apply to all the suspicious cases of APE. This method was valuable in diagnosis of the disease. The anticoagulant therapy was applied in 14 cases, in which heparin was used. One case died in hospital, the fatality rate was 7.14% . Non-heparin therapy was applied in 16 cases. Five cases died and the fatality rate was 31.25% ,which was obviously higher than heparin therapy cases(F<0.05). It was indicated that the heparin anticoagulant therapy had a remarkable effect in acute stage of APE.