经尿道前列腺等离子汽化电切联合间断雄激素阻断治疗晚期前列腺癌

Transurethral electrovaporization ablation of the prostate combined with intermittent androgen blockade in the management of advanced prostatic cancer

目的:探讨经尿道前列腺电切术联合间断雄激素阻断治疗前列腺癌的临床疗效。方法:回顾分析我院为24例确诊为合并膀胱出口梗阻晚期前列腺癌患者行经尿道前列腺等离子汽化加全间断雄激素阻断术的临床资料。结果:24例手术均获成功,术中出血少,术后随访12个月,术后3个月国际前列腺症状评分(7.12±4.24),生活质量评分(1.8±0.4),残余尿(26.5±12.2)ml,最大尿流率(17.82±2.78)ml/s,血清PSA平均(6.3±2.1)ng/ml。结论:等离子汽化电切加间断雄激素阻断治疗能提高合并膀胱出口梗阻晚期前列腺癌患者的生存质量。

Objective：To investigate the efficacy of transurethral electrovaporization ablation of the prostate（TUVP） combined with intermittent androgen blockade（IAB） for advanced prostatic cancer.Methods：The clinical data of 24 cases diagnosed as prostatic cancer complicated with bladder outlet obstruction（BOO） and treated with TUVP combined by IAB were collected and analyzed retrospectively.Results：All the operations were successfully performed and the blood loss was little.3 months after the operation,the international prostate symptom score （IPSS） was （ 7.12 ±4.24 ）, quality of life （QOL） was （ 1.8 ±0. 4 ）, the average of residual urine was（26.5 ±12.2）ml,the average of maximum of uroflowmetry was （ 17.82 ±2.78） ml/s,and average of PSA was （6.3 ±2.1） ng/ml. Condusions：TUVP combined with IAB is a safe and efficient therapeutic option to relieve BOO due to advanced prostate cancer.