血液病患者输血与庚型肝炎病毒感染的研究

Study on hepatitis G virus infection in 63 posttransfusion patients with hematological diseases

目的：了解血液病患者输血后的庚型肝炎病毒（ＨＧＶ）感染情况。方法：对６３例血液病患者采用ＲＴＰＣＲ方法检测ＨＧＶＲＮＡ、丙型肝炎病毒（ＨＣＶ）ＲＮＡ，应用ＥＬＩＳＡ方法检测抗ＨＧＶ、ＨＢｓＡｇ。结果：ＨＧＶＲＮＡ阳性率为７．９％，抗ＨＧＶ阳性率６．３％；ＨＣＶＲＮＡ阳性率为４６．０％。ＨＧＶ感染通常伴有ＨＣＶ感染及丙氨酸转氨酶升高。ＨＧＶ感染与输血量有关，与血液病种类无关。结论：血液病输血可引起ＨＣＶ。

Objective: To study the hepatitis G virus(HGV) infection in posttransfusion patients. Methods: HGV RNA and HCV RNA were detected by RT PCR, and anti HGV and HBsAg were assayed by ELISA in 63 posttransfusion patients with blood diseases. Results: The positive rates of HGV RNA, HCV RNA and anti HGV were 7.9%, 46.0% and 6.3%, respectively. HGV infection was usually accompanied by HCV infection and elevation of ALT. Conclusion: HGV as well as HCV may transmitted by blood transfusion.