食管贲门癌患者红细胞免疫功能检测及其临床意义

Erythrocyte Immune Functions and Its Clinical Significance in Patients with Esophageal and Cardiac Carcinoma

为了解食管贲门癌病人红细胞免疫功能的变化及其临床意义，对３０例病人和对照组２０例非肿瘤病人进行红细胞免疫功能检测，并与对照组及手术前后相比较。结果显示：食管贲门癌患者术前红细胞Ｃ３ｂ受体花环率（ＲＢＣＣ３ｂＲＲ）降低，循环免疫复合物含量（ＣＩＣ）增高，Ｐ＜０．０１。术后与术前相比有明显改善，Ｐ＜０．０１，接近对照组水平。可以认为红细胞免疫功能的变化可作为食管贲门癌病人辅助诊断、预后监测和疗效判断的一项免疫学参考指标。

The erythrocyte immune functions of 30 cases of esophageal or cardiac cancer and 20 controls were examined in pre operation and postoperation.The results showed that compared with controls,the RBC C 3b RR formation rate was lower and CIC content was higher in cancer cases( P <0.01).After operation the above data changed and closed on the levels in controls.The authors suggest that the changes of erythrocyte immune functions may act as an immune parameter for diagnosis and prognostic monitor of esophageal or cardiac cancer.