注射用甘草酸单铵S细菌内毒素检测方法的研究

Study on testing method for bacterial endotoxin in Compound Ammonium Glycyrrhetate S for Injection

目的建立复方甘草酸单铵S的细菌内毒素检查方法。方法参照《中国药典》2005年版(二部)细菌内毒素检查法进行试验。结果样品浓度为0.07mg.mL-1,不干扰细菌内毒素试验。结论该产品采用细菌内毒素检查是可行的。

OBJECTIVE To establish a method for bacteria endotoxin test of Compound Ammonium Glycyrrhetate S for Injection.METHODS Experiment was conducted according to bacteria endotoxin test in China Pharmacopeia 2005,second section.RESULTS 0.07 mg·mL-1 solution of Compound Ammonium Glycyrrhetate S for Injection did not interfere with bacteria endotoxin test.CONCLUSION It is feasible for Compound Ammonium Glycyrrhetate S for Injection conducted bacteria endotoxin.