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冠心病患者叶酸治疗前后血浆同型半胱氨酸水平的临床分析

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摘要 目的观察68例冠心病(coronary heart disease,CHD)患者叶酸治疗前后血浆同型半胱氨酸水平变化。方法据定量冠状动脉造影(QCA)结果,确诊68例CHD患者为实验组,其中不稳定型心绞痛(UAP)组47例,心肌梗死(MI)组21例,46健康体检者例为对照组(CON)组;68例CHD患者随机分为叶酸治疗组(A)38例和非治疗组(B)30例。用酶联免疫分析法(ELISA)检测并分析两组血浆中Hcy水平,以及分析CHD患者叶酸治疗组和非治疗组血浆中Hcy水平。结果CHD组血浆中Hcy水平明显高于CON组(P<0.05),经叶酸治疗后CHD组患者血浆中Hcy水平明显下降(P<0.05)。结论冠心病患者血浆中Hcy水平明显高于正常,经叶酸治疗后血浆中Hcy水平明显降低。
作者 孙珺 刘彦春 高铭枢
机构地区 大同市第三人民医院
出处 《齐鲁药事》 2009年第9期539-540,共2页 qilu pharmaceutical affairs
关键词 冠心病 同型半胱氨酸 定量冠状动脉造影 叶酸
分类号 R969.1 [医药卫生—药理学]
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参考文献6

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齐鲁药事
2009年 第9期

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