摘要
目的分析韶关市近6年来新生儿先天性甲状腺功能低下症(CH)的筛查情况和发病率。方法新生儿出生72h充分哺乳6次后足跟采血,滴在特殊的滤纸(美国S﹠S903滤纸)片上,用时间分辨荧光免疫分析法测定促甲状腺素浓度。TSH≥10.0U/L,通知原采血单位立即召回再采血复查,结果仍超过10.0U/L,由本院直接召回抽血确诊。结果6年共筛查新生儿77220例,可疑阳性患儿572例,确诊33例,发病率为1/2340。结论韶关市新生儿CH发病率高于全国统计率,可能与环境因素及饮食习惯有关。
Objective To analysis incidence of congenital hypothyroidism (CH) in newborns in Shaoguan city. Methods Thyroid stimulating hormone (TSH) screening for CH was done in newborns of 72 hours or after six thoroughly suckling. Three drops of blood were taken from heels of newborns to the Filter papers, then the values of TSH were measured by time-resolved fluoroimmuno assay. Infants with TSH ≥ 10.0 U/L were recalled for tests by blood collection unit, and if the tests were also exceed 10.0 U/L, the infants were recalled for tests by our hospital. Results 77 220 filter paper samples were tested. 572 Infants with suspected CH and 33 Infants were confirmed with CH. Incidence of CH was 1/2 340 in shaoguan. Conclusion The incidence of CH in Shaoguan is higher than the average level of the whole country. This may be related to environment and diet.
出处
《热带医学杂志》
CAS
2009年第9期1049-1050,共2页
Journal of Tropical Medicine