皮层体感诱发电位术中监护脊髓损伤的实验研究

Experimental study on cortical somatosensory evoked potential monitoring spinal cord injury during operation

目的：为开展皮层体感诱发电位（ＣＳＥＰ）术中监护脊髓损伤，判断损伤程度及确定脊髓损伤的警戒线。方法：采用４２只家犬，分别造成静压型和加速压迫型脊髓损伤，术中ＣＳＥＰ动态监测，并观察术后１～３个月脊髓功能恢复情况。结果：静压３０分钟所造成的脊髓损伤，虽然波幅较术前下降１００％，并无危险，若能及时彻底解除压迫，脊髓功能日后可基本恢复正常。加速压迫型脊髓损伤ＣＳＥＰ术中监护安全范围是Ｐ１潜伏期较术前延长不超过１．５倍，波幅下降＜５０％。结论：ＣＳＥＰ术中监护脊髓损伤准确可靠，为成功地用于临床提供了依据。

Objective: To discuss the using of cortical somatosensory evoked potential (CSEP) monitoring spinal cord injury in operation. Methods: This study was carried out in 42 dogs. The spinal cord injury was caused by static pressure and accelerative compression respectively. The spinal cord function was monitored by CSEP during and 1 to 3 months after operation. Results: The spinal cord injury which was caused by static perssure 30 minutes had not danger, although P 1 latency extended 2 02 times. even wave amplitued falled to 100%. If the compression was thoroughly removed in time, the spinal cord function could return to normal in later. The CSEP security lines of spinal cord injury caused by accelerative compression were that P 1 latency prolonging less than 1 5 times and the amplitued falling less than 50%. Conclusion: CSEP monitoring spinal cord injury during operation is accurate and reliable. It provides scientific basis for clinical application.