早期介入治疗对非ST段抬高性急性冠脉综合征患者生存率的影响

Effect of Early Interventional Therapy on Survival Rate in Patients with Non-ST-segment Elevation Acute Coronary Syndrome

目的探讨早期介入治疗对辽宁地区非ST段抬高性急性冠脉综合征患者生存率的影响。方法自2006年3月至2007年1月入院并接受介入治疗的非ST段抬高急性冠脉综合征患者226例,男153例,女73例,平均年龄(61.1±10.7)岁。分为入院48 h内介入治疗组和入院48 h后介入治疗组。通过门诊、病历记录或电话随访,随访30 d、90 d、180 d的心血管事件(包括心脏性死亡、非致命性心肌梗死、非致命性心力衰竭、缺血性心绞痛)。结果入院48 h内介入治疗组、48 h后介入治疗组患者基线特征比较:入院48 h内介入治疗组患者年龄(59.2±10.1)岁,48 h后介入治疗组(63.1±10.9)岁,两组比较差异显著(P<0.01);两组出院后180 d生存率比较无显著差异(P>0.05)。结论入院48 h内的介入治疗与入院48 h后的介入治疗对辽宁地区非ST段抬高性急性冠脉综合征患者的出院后180 d生存率的影响无明显差别。

Objective To study the effect of early interventional therapy on the survival rate in patients with non-ST-segment elevation acute coronary syndrome. Methods Totally 226 patients （including 153 men and 73 women,with a mean age of 61.1±10.7 years） with non-ST- segment elevation acute coronary syndrome who admitted to hospital from March 2006 to January 2007 were included. The patients underwent interventional therapy within 48 hours of admission （group A） or 48 hours after admission （group B ）. The patients were followed up, and the incidences of cardiovascular events 30,100, and 180 days after hospital discharge were recorded. Results The mean ages were 59.2±10.1 years in group A and 63.1±10.9 years in group B,and there was significant difference in the mean age between 2 groups （P = 0.301 ）. No statistically significant difference in the survival rate 180 days after hospital discharge was observed between 2 groups. Conclusion In patients with non-ST-segment elevation acute coronary syndrome, there, is no significant difference in survival rate 180 days after hospital discharge between patients undergoing interventional therapy within 48 hours of admission and those undergoing interventional therapy 48 hours after admission.