腺苷负荷心肌灌注显像141例临床分析

Clinical analysis on 141 cases of adenosine 99mTc-MIBI myocardial perfusion imaging

目的:腺苷负荷心肌灌注显像(MPI)与冠状动脉造影(CAG)2种检查方法的结果对比分析。方法:对141例患者分别行腺苷负荷MPI及CAG检查,并使用校正的TIMI血流分级(CTFC)方法评价冠状动脉血流速度。对2种方法的检查结果进行比较分析。结果:腺苷负荷MPI阳性的99例患者中,经CAG检查确诊冠心病者52例,冠状动脉慢血流(CSF)者37例,冠状动脉正常者10例。腺苷负荷MPI对冠心病诊断的灵敏度和特异度为92.9%和44.7%;对CSF诊断的灵敏度和特异度为82.2%和75.0%。结论:腺苷负荷MPI阳性者中一部分为冠心病患者,一部分为CSF者,对于腺苷负荷MPI异常的患者需进一步行CAG检查以明确病情。

Objective： Comparison the results of adenosine ^99m Tc-MIBI myocardial peffusion imaging（MPI） and coronary angiography（ CAG）. Metbod： 141 patients were examined by adenosine myocardial perfusion imaging and CAG. The duration between two methods were less than two weeks. Coronary flow patterns of the cases were determined by corrected TIMI frame count （CTFC） method. CAG data were compared with adenosine myocardial perfusion imaging. Result： In the 99 cases had positive adenosine myocardial perfusion imaging, 52 patients have severes coronary artery stenosis, 37 have coronary slow flow （CSF） and 10 eases have normal coronary folw confirmed by coronary angiography. The sensitivity and specificity of adenosine myocardial perfusion imaging for the diagnosis of coronary artery disease （CAD） were 92.9% and 44.7%; The sensitivity and specificity of adenosine myocardial perfasion imaging for the diagnosis of CSF were 82.2% and 75.0% . Conclusion：The coronary artery disease and CSF patients both have positive adenosine ^99mTc-MIBI myocardial perfusion imaging. So CAG should performed in the cases, which have positive adenosine ^99mTc-MIBI myocardial perfusion SPECT to comflrm the diagnosis.