更昔洛韦联合外用湿敷煎剂治疗带状疱疹神经痛的疗效观察

Curative Efficacy of Ganciclovir Combined with the Damp Medicine for External Application for Postherpetic Neuralgia

目的:观察更昔洛韦联合外用湿敷煎剂治疗带状疱疹神经痛的临床疗效。方法:将73例带状疱疹神经痛患者随机分为2组:对照组31例,给予更昔洛韦0.25g,静脉滴注;治疗组42例,在对照组治疗的基础上联合外用湿敷煎剂治疗,每日1次,共7d。结果:治疗组治愈14例,显效26例,无效2例,总有效率95.24%;对照组治愈7例,显效17例,无效7例,总有效率77.42%。治疗组总有效率显著高于对照组(P<0.05)。治疗组的皮损消退及疼痛消失时间与对照组比较有显著差异(P<0.01)。结论:更昔洛韦联合外用湿敷煎剂治疗带状疱疹神经痛疗效迅速,患者恢复良好。

OBJECTIVE： To study the curative efficacy of ganciclovir combined with the damp medicine for external application for postherpetic neuralgia. METHODS： 73 cases of postherpetic neuralgia were randomly divided into two groups： 31 cases in the control group were treated with 0.25 g ganiclovir by iv, gtt; 42 cases in treatment group received the same therapy to control group additionally plus the damp medicine for external application once daily for 7 days.RESULTS： In the treatment group, 14 cases cured, 26 cases achieved obvious effect, 2 did not have a response to treatment, and the overall effective rate was 95.24% ; in the control group, 7 cases cured, 17 cases achieved obvious effect and 7 did not have response to the treatment, and the total effective rate was 77.42%, which was significantly lower than in treatment group （P〈0.05）. The duration of cutaneous deficiency disappeared and pain disappeared in treatmemt group was significantly different from that in control group（P〈0.01）. CONCLUSION： Patients with postherpetic neuralgia treated with ganciclovir combined damp medicine for external application showed rapid curative efficacy and good recovery.