摘要
The intensive lipid-lowering and the anti-inflammatory effect are the new perspective of statin application in current clinic practice. Patients with coronary heart disease, regardless of lipid levels, should receive lipid-lowering treatment; even those people who have the ＂normal＂ blood lipid level may also require lipid-lowering therapy. While the mainstream view was that the clinical benefit of statins was mainly due to the reduction of the LDL-C level, those effects other than lipid-lowering of statins are of more and more importance. In particularly, the anti-inflammatory effect of statins is evidence-based and has become a new point of view that makes people take more and more attention. We look forward to the new evidence-based information and the new available guidelines. In any case, we believe that the era for the primary prevention with anti-inflammatory effect of statins may have already started.
The intensive lipid-lowering and the anti-inflammatory effect are the new perspective of statin application in current clinic practice. Patients with coronary heart disease, regardless of lipid levels, should receive lipid-lowering treatment; even those people who have the ＂normal＂ blood lipid level may also require lipid-lowering therapy. While the mainstream view was that the clinical benefit of statins was mainly due to the reduction of the LDL-C level, those effects other than lipid-lowering of statins are of more and more importance. In particularly, the anti-inflammatory effect of statins is evidence-based and has become a new point of view that makes people take more and more attention. We look forward to the new evidence-based information and the new available guidelines. In any case, we believe that the era for the primary prevention with anti-inflammatory effect of statins may have already started.
