原发性中枢神经系统淋巴瘤的MRI诊断与鉴别诊断

MRI diagnosis and differentiation of primary central nervous system lymphoma

目的分析原发性中枢神经系统淋巴瘤（PCNSL）的MRI表现，以提高其诊断正确性。方法回顾性分析8例经手术病理证实的PCNSL的MRI资料。结果单发7例，多发1例；8例均位于幕上。T1WI及T2WI与脑灰质信号相近，瘤周水肿轻度4例，中度3例，重度1例。增强后病灶明显强化，呈团块状或分叶状。结论PCNSL的MRI表现有一定特征性，结合临床资料认真分析病变，误诊可以明显减少。

Objective To analyze MRI findings of primary central nervous system lymphoma（ PCNSL）, and improve the accuracy of diagnosis. Methods MRI findings of 8 patients with primary central nervous system lymphoma confirmed by operation and pathology were analyzed retrospectively. Results Seven patients with single lesion were found and 1 patient with multiple lesions. The lesions of 8 patients were all located at supratentoriai region. The signals of all lesions were homogeneous and similar to grey matter on both TI and T2 - weighted images. Slight para - tumorous edema was found in 4 patients, moderate edema in 3 patients and marked edema in 1 patient. Following Gd - DTPA administration,the lesions presented obviously mass - like or nodular enhancement. Conclusions Primary central nervous system lymphoma have typical MRI features. Misdiagnosis can be reduced greatly if enough attention is paid to the analysis of the MRI features.