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细菌性肺炎患儿血清降钙素原与C反应蛋白的测定及其临床意义 被引量:3

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摘要 目的探讨细菌性肺炎患儿血清降钙素原(PCT)与C反应蛋白(CRP)水平的改变及其临床意义。方法以62例细菌性肺炎患儿(其中轻症32例,重症30例)和25例健康体检儿童(对照组)为研究对象,采用发光免疫分析法、免疫透射比浊法分别测定血清PCT、CRP水平。结果重症细菌性肺炎患儿血清PCT值均高于0.5mg/L。细菌性肺炎急性期患儿血清PCT水平明显高于对照组(P〈0.01)。轻症与重症细菌性肺炎急性期患儿间比较,CRP值差异无显著性(P〉0.05),PCT值差异有显著性(P〈0.01)。急性期与恢复期细菌性肺炎患儿比较,PCT、CRP值差异均有显著性(P〈0.01)。结论血清PCT可用于早期细菌感染诊断,并可作为判断细菌感染轻重的一个生化指标,联合检测CRP水平变化有利于病情监测和疗效评价。
出处 《中国小儿急救医学》 CAS 2009年第5期469-470,共2页 Chinese Pediatric Emergency Medicine
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